Open AccessEffectively degradation of trace cytostatic drug capecitabine in water using porous Ti/SnO2-Sb/Ce-PbO2 as a reactive electrochemical membrane
Author(s) -
Lei Xu,
Xiao Ma,
Jinhua Wu
Publication year - 2020
Publication title -
iop conference series. earth and environmental science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.179
H-Index - 26
eISSN - 1755-1307
pISSN - 1755-1315
DOI - 10.1088/1755-1315/508/1/012128
Subject(s) - degradation (telecommunications) , electrochemistry , anode , kinetics , capecitabine , membrane , porosity , materials science , reaction rate constant , chemistry , chemical engineering , electrode , composite material , medicine , telecommunications , biochemistry , colorectal cancer , cancer , computer science , engineering , physics , quantum mechanics
The electrochemical degradation kinetics of trace cytostatic drug capecitabine (CAP) at a concentration of 10 μg/L were investigated with a porous flow-through membrane anode. Electrochemical degradation of trace CAP followed the pseudo-first-order reaction kinetics. The kinetic rate constant ( k ) of 0.111 min −1 was found under optimal conditions. Higher current density and Cl − concentration benefited CAP degradation. The reactive electrochemical membrane was proved to be effective for the degradation of trace CAP in water.