Open AccessEffect of Black Tea (camellia sinensis) on Serum Adiponectin Level in Atherogenic Diet Rats
Author(s) -
Ebti Rizki Utami,
Meity Ardiana,
Bayu Lestari,
Endang Sri Wahyuni,
Edy Widjajanto,
R Rizkiawan
Publication year - 2020
Publication title -
iop conference series. earth and environmental science
Language(s) - English
Resource type - Journals
eISSN - 1755-1307
pISSN - 1755-1315
DOI - 10.1088/1755-1315/441/1/012169
Subject(s) - adiponectin , black tea , medicine , analysis of variance , one way analysis of variance , endocrinology , camellia sinensis , biology , obesity , botany , food science , insulin resistance
The aim of this study is to investigate the effect of black tea administration on serum adiponectin level in male Wistar fed with atherogenic diet (AD). This study was designed as a true experimental design that assigns 20 rats, and divides them into four groups as follows: P1 (AD 3 months); P2, P3, and P4 (3 months AD + black tea extract administration at dosage 0.015gr/day, 0.03gr/day, 0.045gr/day, respectively). Serum adiponectin level was measured using ELISA method. This study demonstrated that there is an elevation trend of adiponectin level as the dose elevated. However, serum adiponectin level in AD-only group (380.6ng/mL) was not significantly different with treatment group (386.93ng/mL, 404.27ng/mL, and 416.6ng/mL in P2, P3, and P4, respectively) (ANOVA, p = 0.352). Furthermore, there was no significant association between the dosage of black tea and adiponectin levels (Pearson correlation test, p = 0.073, r = 0.373). We concluded that black tea extract increased serum adiponectin level insignificantly in atherogenic diet rats.