Open AccessCorrelation between Osteoprotegerin Serum Levels and Arterial Stiffness Assessed by Cardio-ankle Vascular Index (CAVI) in Hypertensive Patients
Author(s) -
A Ariendanie,
Johanes Nugroho Eko Putranto,
I G N I R Ranuh
Publication year - 2020
Publication title -
iop conference series. earth and environmental science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.179
H-Index - 26
eISSN - 1755-1307
pISSN - 1755-1315
DOI - 10.1088/1755-1315/441/1/012158
Subject(s) - osteoprotegerin , arterial stiffness , medicine , cardiology , ankle , aorta , blood pressure , surgery , receptor , activator (genetics)
The cardio-ankle vascular index (CAVI) is a newly developed clinical measurement for evaluating arterial stiffness from the origin of the aorta to the ankle. Osteoprotegerin (OPG) is widely known as a vascular calcification mediator, which have a role to affect atherogenesis. Thirty subjects participated in this research and each subject underwent a CAVI examination to assess arterial stiffness and their blood samples were collected for OPG measurement. This study is analyzed with Pearson Correlation Test. There is a positive, strong and significant correlation between osteoprotegerin serum level and arterial stiffness using Cardio-Ankle Vascular Index (CAVI) in hypertensive patients. (r = 0.730 and p <0,0001). There was a positive, strong and significant correlation between osteoprotegerin serum level and arterial stiffness using Cardio-Ankle Vascular Index (CAVI) in hypertensive patients.