Open AccessEthnomedicine, phytochemical, and toxicity activity of several alleged medicinal plants from Sebangau National Park, Central Borneo
Author(s) -
Gunawan Pasaribu,
T. K. Waluyo
Publication year - 2020
Publication title -
iop conference series. earth and environmental science
Language(s) - English
Resource type - Journals
eISSN - 1755-1307
pISSN - 1755-1315
DOI - 10.1088/1755-1315/415/1/012007
Subject(s) - phytochemical , traditional medicine , ethnomedicine , antimicrobial , medicinal plants , acute toxicity , phytomedicine , palmitic acid , biology , chemistry , toxicity , medicine , fatty acid , biochemistry , microbiology and biotechnology , organic chemistry
Indonesia is a country endowed with its abundant biodiversity; and therefore potential in providing future drugs derived from renewable natural materials (e.g. plants). Relevantly, this study aimed to identify and analyze the ethnomedicine, phytochemical, toxicity, and active compounds of several alleged medicinal plant species from Borneo. Results showed local people used those plants to cure various diseases or other human physiological disorders, such as antidote, varices, liver medicine, tonsil medicine, stomachache, diarrhea, sprue medicine, itching, ulcers antihypertension and malaria. Those plants as examined generally contained tannins, saponins, flavonoids, and triterpenoids. Some of them contained alkaloids. Toxicity tests, as represented by LC 50 values, exhibited their range from 126.70 to 883.34 ppm. Further, various chemical compounds such as trans-caryophyllene and veridiflorol effectively inflicted a significant effect as antimicrobial, antifungal, and antibiotics. Fatty acids such as hexadecanoic acid, palmitic acid, linoleic acid, octadecadienoic acid, and stearic acid could inhibit the growth of microbes. Phenolic compounds could acts as an antioxidant and antidiabetic. Judging from all the varying LC50 values, ethnobotany-related explorations, and other biomedical/biochemical tests, those analyzed species could be strongly judged as efficacious medicinal plants; and therefore potentially developed as raw material for herbal drugs.