Open AccessPharmacological improvement of metabolic processes in piglets in a state of postnatal physiological immaturity
Author(s) -
А. И. Кузнецов,
Natalya Smolyakova,
И. А. Лыкасова,
Ф Г Гизатуллина
Publication year - 2019
Publication title -
iop conference series. earth and environmental science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.179
H-Index - 26
eISSN - 1755-1307
pISSN - 1755-1315
DOI - 10.1088/1755-1315/341/1/012058
Subject(s) - oxidative phosphorylation , riboflavin , respiration , lactic acid , succinic acid , biology , mitochondrion , biochemistry , potassium , chemistry , anatomy , bacteria , genetics , organic chemistry
The article presents results of the development of a method for improving metabolic processes in immature piglets. In order to achieve the purpose of the research, pharmacological preparations were selected taking into account the nature of changes in metabolic processes in piglets in a state of acquired immaturity. For this purpose, effects of riboflavin, Vicasol, potassium succinic acid and their combinations were determined separately. It was established that feeding immature piglets with acid potassium (0.125 g) combined with riboflavin (2.5 mg) and vicasol (0.3 g) for 18-21 days improves metabolic processes, ensures the growth and development of animals. Increased development of macroergs decreases the levels of lactic acid and fatty acids, restores semipermeable properties of cell membranes and mitochondria, improves the conjugation of respiration processes with oxidative phosphorylation. Metabolic processes become improved; values of the parameters reach those of mature animals. The method of improvement of metabolic processes in piglets in a state of postnatal immaturity is simple, does not require special equipment and technology. Its implementation removes 100% of the animals from the state of immaturity and increases their live weight by 42.8; the average daily gain is 33.1, the safety level is 39.7%.