Open AccessDelivery carrier of curcumin based on nanotechnology : A review
Author(s) -
Dawei Zong
Publication year - 2019
Publication title -
iop conference series. earth and environmental science
Language(s) - English
Resource type - Journals
eISSN - 1755-1307
pISSN - 1755-1315
DOI - 10.1088/1755-1315/332/3/032016
Subject(s) - curcumin , bioavailability , chemistry , nanoparticle , functional food , solubility , nanotechnology , polyphenol , pharmacology , antioxidant , materials science , biochemistry , medicine , food science , organic chemistry
Curcumin is a polyphenolic compound derived from the rhizome of turmeric. It has been widely used as a medicine, condiment and food additives. Curcumin has several biological activities such as anti-oxidation, anti-inflammatory, liver protection, anti-tumor, anti-atherosclerosis, inhibition of obesity, anti-aging, neuroprotection, and anti-senile dementia, it has been applied in functional food in recent years. In view of the current shortcomings of curcumin, such as poor water solubility, instability, and low bioavailability, improving its bioavailability will be the main research direction in the future. This paper mainly discussed the source and physicochemical properties of curcumin, as well as the research progress of delivery carrier of curcumin including nanoparticles of protein matrix, nanoparticles of polysaccharide matrix and nanoparticles of protein polysaccharide composite matrix. Besides, it discussed the application of nanoparticles in improving the solubility, stability, and bioavailability of curcumin. The paper might contribute to the development and research of functional food.