Open AccessAntioxidant Activity of Haramounting Leaf Ethanol Extract (Rhodomytrus tomentosa) In Preventing Heart Damage of Mice (Mus musculusL.) after exposure to Electronic Cigarette
Author(s) -
Syafruddin Ilyas,
Rendra Syahputra Tanjung,
Salomo Hutahaean,
Masitta Tanjung,
Elimasni,
It Jamilah,
Finn Murdela
Publication year - 2019
Publication title -
iop conference series. earth and environmental science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.179
H-Index - 26
eISSN - 1755-1307
pISSN - 1755-1315
DOI - 10.1088/1755-1315/305/1/012080
Subject(s) - antioxidant , ethanol , h&e stain , smoke , histology , staining , randomized block design , traditional medicine , cigarette smoke , body weight , chemistry , pharmacology , medicine , food science , physiology , biology , toxicology , pathology , biochemistry , horticulture , organic chemistry
Cigarette smoke is one factor that increases free radicals in the blood will affect liver health in the body. The purpose of this study is to find outthe effect of giving leaves ethanol extract haramounting to histology of male mice liver exposed to electric cigarettes. The design of this study used Completely Randomized Design (CRD) consisting of + Group, - Group and three treatments of Haramounting Leaf Ethanol Extract (Rhodomyrtus tomentosa (Aiton) Hassk.) for 30 days at a dose of 100 mg/kg BW Body Weight, 200 mg/kg BW and 300 mg/kg BW for treament use of five replications. Liver organ preparations were made using paraffin block method and Hematoxylin Erlich-Eosin (HE) staining. The results of the study show on histological observations The liver has a tendency that electric cigarette smoke can cause damage in liver cells. The results of this study indicate that ethanol extract leaves of Haramounting after exposure to eletric cigarette smoke can effectively regenerate damaged liver cells.