Open AccessIn Silico Studies in Antimicrobial Peptides Design and Development
Author(s) -
Tristia Rinanda
Publication year - 2019
Publication title -
iop conference series. earth and environmental science
Language(s) - English
Resource type - Journals
eISSN - 1755-1307
pISSN - 1755-1315
DOI - 10.1088/1755-1315/305/1/012062
Subject(s) - in silico , antimicrobial peptides , antimicrobial , computational biology , computer science , biology , biochemical engineering , engineering , microbiology and biotechnology , biochemistry , gene
Antimicrobial peptides (AMPs) are a group of natural-derived molecules exhibited broad spectrum antimicrobial activity. Currently these molecules have been investigated comprehensively due to their interesting features regarding antimicrobial and immunomodulatory mode of actions which placed them as promising therapeutics agents in this post antibiotics era. Numerous strategies have been implemented in order to develop a novel AMP for biotechnology and therapeutics applications, one of which is in silico study.. This approach offers a rapid and cost effective manner in AMPs design and development. In silico studies provide additional and substantial information for in vitro techniques. In this paper, we deliver an overview of the applicable in silico approaches that have been used in designing and developing AMPs.