Open AccessDevelopment of graphene-chitosan composite modified screen-printed carbon electrode and its application for detection of rutin
Author(s) -
Wulan Tri Wahyuni,
Zulhan Arif,
Noroozi Maryam
Publication year - 2019
Publication title -
iop conference series. earth and environmental science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.179
H-Index - 26
eISSN - 1755-1307
pISSN - 1755-1315
DOI - 10.1088/1755-1315/299/1/012005
Subject(s) - rutin , detection limit , graphene , graphite , electrode , materials science , chemistry , analytical chemistry (journal) , nuclear chemistry , chromatography , nanotechnology , composite material , antioxidant , biochemistry
Graphene is a prospective material for sensing devices due to its excellent electronic, thermal, and mechanical properties. In this study, low oxygen graphene was synthesized from graphite and nitronium ion using a microwave-assisted method. Graphene was dispersed into 0.05% chitosan solution and deposited by drop casting method on to screen-printed carbon electrode (SPCE) to form graphene-chitosan composite modified SPCE (SPCE-G-chit). The electrochemical performance of SPCE-G-chit was evaluated using flavonoid 3’,4’,5,7-tetrahydroxyflavone-3β-D-rutinoside (rutin). SPCE-G-chit provides linearity with R 2 of 0.9944 for rutin measurement in the concentration range of 5× 10 −7 to 1× 10 −5 M. Meanwhile, the linearity of rutin at SPCE was lower ( R 2 0.9396). Limit of detection (LOD) and limit of quantitation (LOQ) of rutin measurement at SPCE-G-chit was lower (0.23 µM and 0.58 µM, respectively) compare to SPCE (LOD = 0.69 µM and LOQ = 1.75 µM, consecutively). The accuracy of rutin measurement at SPCE-G-chit was 99.45% while the accuracy of rutin measurement at SPCE was 72.18%. The result indicated that SPCE-G-chit provides superior analytical performance than SPCE and potential for electrochemical sensor development.