
Synthesis, characterization and biological studies of some new organometallic compounds containing mercury, selenium and tellurium based on p-aminobenzoic acid
Author(s) -
Ali Z. AlRubaie,
Shaker A. S. Al-Jadaan,
Anwar T. Abd Al-Wahed,
Ibraheem A Raadah
Publication year - 2021
Publication title -
journal of physics. conference series
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 85
eISSN - 1742-6596
pISSN - 1742-6588
DOI - 10.1088/1742-6596/2063/1/012003
Subject(s) - selenide , chemistry , selenium , tellurium , chloride , mercury (programming language) , diselenide , telluride , diphenyl diselenide , chalcogen , antibacterial activity , escherichia coli , organic chemistry , nuclear chemistry , medicinal chemistry , bacteria , stereochemistry , biochemistry , biology , computer science , gene , genetics , programming language
Ten chalcogen and mercury bearing compounds based on 4-aminobenzoic acid ( i.e. , (2-amino-5-(ethoxycarbonyl)phenyl)mercury(II) chloride (1), (2-amino-5-(ethoxycarbonyl)phenyl) phenyl selenide (2), (2-amino-5-(ethoxycarbonyl)phenyl) phenyl telluride (3), (4-carboxyphenyl)mercury(II) chloride (4), 4-selenocyanatobenzoic acid (5), 4-tellurocyanatobenzoic acid (6), bis(4-carboxyphenyl) diselenide (7) bis(4-carboxyphenyl) ditelluride (8), bis(4-carboxyphenyl) selenide (9) bis(4-carboxyphenyl) telluride (10) were prepared and characterized by various spectroscopic techniques. All compounds were screened for antibacterial activity against Gram-positive bacterial strains of Staphylococcus aureus and the Gram-negative bacteria Escherichia coli by using the disk diffusion technique. The antibacterial activity of these compounds was dependent on the molecular structure of the compounds, and the bacterial strain under consideration.