Open AccessThe H2O2treated agarose compositing with gelatin for skin repair
Author(s) -
Tianyi Tang,
Bin Cui,
Jialin Cao,
Shunqing Tang
Publication year - 2021
Publication title -
journal of physics. conference series
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 85
eISSN - 1742-6596
pISSN - 1742-6588
DOI - 10.1088/1742-6596/1980/1/012016
Subject(s) - gelatin , agarose , mixing (physics) , compositing , materials science , matrix (chemical analysis) , staining , eosin , chromatography , biomedical engineering , chemistry , biochemistry , medicine , pathology , physics , quantum mechanics , artificial intelligence , computer science , image (mathematics)
This paper presented that the H 2 O 2 treated agarose ( abbr . AG) was composited with gelatin ( abbr .Gel) as gel-like polymeric mixture for skin cut repair. The low molecular weight AG was prepared by H 2 O 2 treatment for certain intervals. The time of AG gelling might be tested by scattered light turbidimeter and its mechanical properties were evaluated. The degraded AG mixing with Gel was sprayed to cover rabbit lesion site. AG/Gel mixing gel had good biocomptability and could repair rabbit skin wound without liquid exudation and bacterium infection. H&E staining results disclosed that type I collagen and other extracelluar matrix in the repaired site have same with the original skin. The degraded AG mixing with Gel gels have potential as wound dressings.