Open AccessLow-cost Fabrication of PDMS Microfluidic Chamber using Digital Cutter Machine
Author(s) -
Isa Anshori,
Suksmandhira Harimurti,
Michelle Hartono,
Raih Rona Althof,
Lavita Nuraviana Rizalputri,
Murni Handayani,
Tati L. R. Mengko,
Brian Yuliarto
Publication year - 2021
Publication title -
journal of physics. conference series
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 85
eISSN - 1742-6596
pISSN - 1742-6588
DOI - 10.1088/1742-6596/1912/1/012021
Subject(s) - microfluidics , fabrication , materials science , photolithography , lab on a chip , nanotechnology , channel (broadcasting) , chip , optoelectronics , electrical engineering , engineering , medicine , alternative medicine , pathology
Microfluidic chamber or channel is one important tool in the lab-on-a-chip (LoC) technology, which usually serves as a platform to contain liquid analytes. The conventional method to fabricate microfluidic chamber is based on photolithography technique. However, it is a high-cost process and requires special equipment, such as mask aligners and expensive photosensitive resist material. In this work, we fabricated the microfluidic chamber and channel using a much simpler and lower-cost technique that is using PDMS as the main material and polyimide tape as the mold. Using this method, the diameter of the microfluidic pattern (channel/chamber) could be made up to as small as 1 mm and the height of the flow channel was down to tens or hundreds of μm scale-depending on the thickness of the tape. The flow test results showed that low cost and simple microfluidic fabrication method had a good performance and could potentially be further used for real analyte flow test.