Open AccessToxicity Test of Mathanol Fraction of Mentawan (Poikilospermum suaveolens Blume Merr) Stem Which Has Potential as Anticancer
Author(s) -
Pince Salempa,
Diena Pratiwi,
Ramdani Ramdani
Publication year - 2021
Publication title -
journal of physics. conference series
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 85
eISSN - 1742-6596
pISSN - 1742-6588
DOI - 10.1088/1742-6596/1899/1/012037
Subject(s) - brine shrimp , artemia salina , traditional medicine , biology , urticaceae , toxicity , acute toxicity , botany , toxicology , chemistry , medicine , organic chemistry
Mentawan plant ( Poikilospermum suaveolens Blume Merr) is a species of the genus poikilospermum, including the urticaceae family, which is traditionally used by the community for medicine. This plant has the ability to treat eye diseases, fever, malaria and itching and has the potential as an anticancer. This research method includes extraction, fractionation, and fraction bioactivity test with the brine shrimp lethality test (BSLT) against Artemia salina . From the results of the toxicity test using the BSLT method, the activity of methanol fractions with LC 50 values were 4,8752; 62,8492; 85,5460; 45,7088; 28,1838; 11,985; 33.2123 µg / mL. Based on the LC 50 value, it could be concluded that mentawan plant has potential as anticancer.