Open AccessRecent Progress of Polymer Micelles used as Anti-cancer Multifunctional Nano-carriers
Author(s) -
Qian Zhang
Publication year - 2021
Publication title -
journal of physics. conference series
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 85
eISSN - 1742-6596
pISSN - 1742-6588
DOI - 10.1088/1742-6596/1885/3/032049
Subject(s) - micelle , nanotechnology , polyethylene glycol , drug delivery , polymer , photothermal therapy , materials science , amphiphile , anticancer drug , drug carrier , drug , chemistry , organic chemistry , copolymer , medicine , pharmacology , aqueous solution , composite material
Polymer micelles, formed mostly by core-shell structures, are one kind of nano-carriers, which are used in the therapy of cancer through diverse methods. The shell is usually formed by polyethylene glycol (PEG) thus having the advantage of preparing amphiphilic and biocompatible drug-carriers. With different drugs as the core, multi-functions such as magnetic thermal, photothermal, targeting, contrast etc. were discovered to be used in the therapeutic system. Simultaneously, the loading and delivery of drugs can be adjusted under the control of polymer micelles, so that drug-releasing in vivo is enabled to be quantified, accompanied by the change of external conditions in the sake for reduction of cytotoxicity. Therefore, polymer micelles have crucial significance for the treatment of cancer. This essay introduces the latest research progress of polymer micelles to make simple guides for researchers who are getting touched with this field so as to broaden the scope and propose innovations.