Open AccessSynthesis of some new heterocyclic compounds derived from p-chlorobenzoylchloride and investigation of biological effectiveness
Author(s) -
R. M. Abdul-Amir,
N M Abdu Al-Hassan,
H Ghadban
Publication year - 2021
Publication title -
journal of physics. conference series
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 85
eISSN - 1742-6596
pISSN - 1742-6588
DOI - 10.1088/1742-6596/1853/1/012009
Subject(s) - fourier transform infrared spectroscopy , aldehyde , chemistry , ethylenediamine , phosphotungstic acid , infrared spectroscopy , oxazole , nuclear chemistry , organic chemistry , polymer chemistry , catalysis , chemical engineering , engineering
1,3-Oxazole-5-one blends 2(a-c) have been set up by cyclization of compound (1) with aromatic aldehyde auxiliaries. The starting compound (1) was expeditiously procured by the reaction of 4-chlorobenzoylchloride with aminoacetic acid. Blends 2(a-c) were changed over into a grouping of subordinates by the reaction with ethylenediamine to masterminded 3(a-c) by then blends 3(a-c) reaction with aromatic aldehydes subsidiaries to organized 4(a-c). Each new compound was depicted by Proton atomic attractive reverberation ( 1 H-NMR), Fourier changes infrared spectroscopy (FTIR), and Ultraviolet (UV) spectroscopy.