Open AccessSynthesis, characterization, and antioxidant activity of some organotin(IV) 2-nitrobenzoate using the 2,2-diphenyl-1-picryl-hydrazyl (DPPH) method
Author(s) -
Nopitasari,
Tati Suhartati,
. Suharso,
Dian Herasari,
Kamisah Delilawati Pandiangan,
Sutopo Hadi
Publication year - 2021
Publication title -
journal of physics. conference series
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 85
eISSN - 1742-6596
pISSN - 1742-6588
DOI - 10.1088/1742-6596/1751/1/012098
Subject(s) - chemistry , dpph , antioxidant , ascorbic acid , nuclear chemistry , stereochemistry , organic chemistry , food science
Synthesis, characterization, and antioxidant activity of diphenyltin(IV) di-2-nitrobenzoate (2), dibutyltin(IV) di-2-nitrobenzoate (4), and triphenyltin(IV) 2-nitrobenzoate (6) using the 2,2-diphenyl-1-picryl-hydrazyl (DPPH) method has been successfully carried out. All compounds were well characterized by some spectroscopy techniques of UV, IR, NMR and based on physical technique by microelemental analysis. The result showed that diphenyltin(IV) di-2-nitrobenzoate was the most active in the antioxidant activity test, with an IC 50 value of 8.6 μg/mL compared to the other compounds in which the dibutyltin(IV) di-2-nitrobenzoate and triphenyltin(IV) 2-nitrobenzoate have IC 50 values of 12.29 μg/mL and 27.28 μg/mL, respectively, which indicated that compounds 6 and 9 were categorized active antioxidant activity. However the IC 50 values of these compounds were higher than the positive control, ascorbic acid with IC 50 value of 0.66 μg/mL.