Open AccessStudy on Biocompatibility of Chitosan/Hydroxyapatite Doped Silicon Composite as Material for Alveolar Socket Preservation
Author(s) -
María Virginia,
Andromeda Dwi Laksono,
Wentika Putri Kusuma Asih,
Sulistijono,
Diah Tri Agustiningtyas
Publication year - 2021
Publication title -
journal of physics. conference series
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 85
eISSN - 1742-6596
pISSN - 1742-6588
DOI - 10.1088/1742-6596/1726/1/012007
Subject(s) - chitosan , biocompatibility , composite number , antibacterial activity , nuclear chemistry , materials science , chemistry , doping , bacteria , chemical engineering , composite material , metallurgy , organic chemistry , biology , genetics , optoelectronics , engineering
As the Alveolar Socket Preservation (ASP) was developed as a procedure for placement of bone graft on sockets where the tooth was removed, a new composite of Chitosan/Hydroxyapatite doped Silicon (Chi/HAp-Si) was synthesized. Si will be added to HAp in amount 7 wt% by a solid-state method. As a comparison, the HAp-Si later will be mixed with chitosan with variations of 0, 5, 10, and 15 wt%, with the aim of enhancing antibacterial ability against S. aureus bacteria. The synthesized samples were characterized using XRD and SEM. Antibacterial activities of the Chi/HAp-Si composite were evaluated against S. aureus bacteria. The addition of chitosan did not have much effect on the biocompatibility of HAp-Si, especially in S. aureus bacteria. However, the addition of chitosan to the 10 wt% composition has the highest antibacterial properties.