Open AccessEffect of sodium hypochlorite on the structure of nucleic acids studied using infrared spectroscopy
Author(s) -
D N Osinnikova,
E B Moroshkina,
A. M. Polyanichko
Publication year - 2020
Publication title -
journal of physics. conference series
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 85
eISSN - 1742-6596
pISSN - 1742-6588
DOI - 10.1088/1742-6596/1697/1/012047
Subject(s) - sodium hypochlorite , nucleic acid , chemistry , fourier transform infrared spectroscopy , infrared spectroscopy , hypochlorite , sodium , infrared , dna , chemical structure , nuclear chemistry , inorganic chemistry , organic chemistry , biochemistry , chemical engineering , physics , optics , engineering
The effect of sodium hypochlorite (NaClO) on nucleic acids (NAs) was investigated depending on the concentration of the NaClO. We have performed detailed analysis of the FTIR and UV spectra of the NAs incubated with NaClO. It was found that both the destruction of the secondary structure of DNA (denaturation) and the chemical modification of nitrogenous bases occur.