Open AccessC-Ag+−C based repetitive DNA sequence
Author(s) -
Maria A Popova,
V.I. Rolich,
Ruslan R. Ramazanov,
N. A. Kasyanenko,
P. A. Sokolov
Publication year - 2020
Publication title -
journal of physics. conference series
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 85
eISSN - 1742-6596
pISSN - 1742-6588
DOI - 10.1088/1742-6596/1679/2/022049
Subject(s) - nanobiotechnology , nucleobase , dna , crystallography , cytosine , sequence (biology) , nanotechnology , chemistry , dna sequencing , ion , nanostructure , fabrication , atomic force microscopy , materials science , biochemistry , medicine , alternative medicine , pathology , nanoparticle , organic chemistry
DNA is a convenient and well-studied tool for nanostructures fabrication. Metal-mediated hybridization of DNA strands opens up new possibilities for nanobiotechnology. In this work, we studied the possibility of long DNA formation from short ones by gluing them through the formation of C-Ag + −C complexes. Such long formations were investigated using static light scattering and atomic force microscopy. It was found that the duplexes can efficiently be linked in the presence of silver ions if the length of the cytosine sequence exceeds 6 nucleobases.