Open AccessSelenium Nanoparticles And Silymarin To prevent Lead Acetate-Induced Toxicity On Reproductive Performance Of Male Rats
Author(s) -
Rasha Muzahem Hatem,
Eman Mohammed Hussain
Publication year - 2020
Publication title -
journal of physics. conference series
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 85
eISSN - 1742-6596
pISSN - 1742-6588
DOI - 10.1088/1742-6596/1664/1/012104
Subject(s) - lead acetate , selenium , distilled water , toxicity , reproductive toxicity , pharmacology , chemistry , adult male , toxicology , physiology , zoology , traditional medicine , medicine , biology , chromatography , organic chemistry
The current study was carried out to study the effect of selenium nanomaterials and the extract of the silymarin plant on male rats poisoned by lead phastates and to study their effect on male genital. The study was conducted in the eighth month of last year and for 40 days, Where 50 males were taken from rats and were divided equally into 5 groups, which are as follows: Control group 10 animals were gavage with distilled water for 40 days. The lead acetate group was administered in single dose and left for the duration of the experiment. The third group was administered with a single dose of lead acetates and then gavage with selenium nanoparticles for 40 days. The fourth group administered lead acetate with a single dose then gavage with extract of silymarin for 40 days, And the fifth and final group was gavage with lead acetate with a single dose and then administered combination of selenium nanoparticle and extract of silymarin for 40 days. The results of the study exposed that selenium nanotubes and salimarin extract had a positive effect(P < 0.05) on all the parameters measured in this study. In conclusion, SeNPs and extract of silymarin in the supranutritional dose has a positive effect on the reproductive function of male.