Open AccessInhibition of tumor cell proliferation in vitro using atmospheric-pressure plasma jet
Author(s) -
Anastasia A. Evtina,
В. О. Нехорошев,
Mikhail A. Buldakov,
Н. В. Чердынцева,
N. V. Landl,
Yu. D. Korolev
Publication year - 2020
Publication title -
journal of physics. conference series
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 85
eISSN - 1742-6596
pISSN - 1742-6588
DOI - 10.1088/1742-6596/1611/1/012052
Subject(s) - atmospheric pressure plasma , jet (fluid) , plasma , in vitro , tumor cells , atmospheric pressure , chemistry , plasma medicine , biophysics , cancer research , biology , biochemistry , mechanics , physics , meteorology , quantum mechanics
The effect of atmospheric-pressure plasma jet on the proliferative activity of tumor and normal cells was studied. It was shown that under certain parameters, plasma jet inhibits the proliferative activity of tumor cells up to 75%. However, the reaction of normal cells under the same parameters of plasma exposure is different. It was found that low-temperature plasma jet stimulates the proliferative activity of normal cells up to 25% on the 5th day after exposure. The obtained data indicate the prospects of using this low-temperature plasma jet in biomedical research aimed to minimizing the negative impact on healthy tissues during antitumor therapy.