Open AccessSorption activity of polyhexamethylene guanidine hydrochloride hydrogels towards extracts of medicinal plants
Author(s) -
О. С. Очиров,
Д. Н. Оленников,
T A Turtueva,
М. Н. Григорьева,
С А Стельмах,
Д. М. Могнонов
Publication year - 2020
Publication title -
journal of physics. conference series
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 85
eISSN - 1742-6596
pISSN - 1742-6588
DOI - 10.1088/1742-6596/1611/1/012049
Subject(s) - sorption , calendula officinalis , chemistry , guanidine , self healing hydrogels , tincture (heraldry) , hydrochloride , wound healing , traditional medicine , chromatography , nuclear chemistry , organic chemistry , adsorption , medicine , surgery
The study aims to obtain polyhexamethylene guanidine hydrochloride hydrogel compositions with extracts of medicinal plants growing in the Baikal region (Bergenia crassifolia, Calendula officinalis, Tussilago farfara) to evaluate sorption activity and consider the subsequent use of the compositions as an external wound healing agent. It has been shown that hydrogel sorbs mainly caffeinequinic acids in various compositions. It has been made an assumption about a link of sorption process with formation of secondary amino groups’ complex in the hexahydrotriazine cycle, which is formed as a result of gelation of PHMGhch, and carboxyl groups of extract substances. It is planned to study the wound healing activity of compositions by modeling skin damage of laboratory animals in future researches.