Open AccessA voltammetric sensor for simultaneous determination of tryptophan and 5-hydroxytryptophan
Author(s) -
A. M. Altyev,
В. В. Шелковников,
M. S. Fryanova
Publication year - 2020
Publication title -
journal of physics. conference series
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 85
eISSN - 1742-6596
pISSN - 1742-6588
DOI - 10.1088/1742-6596/1611/1/012023
Subject(s) - tryptophan , 5 hydroxytryptophan , electrode , cyclic voltammetry , vitamin b6 , detection limit , carbon nanotube , chemistry , carbon fibers , materials science , electrochemistry , chromatography , nanotechnology , serotonin , vitamin , amino acid , biochemistry , receptor , composite material , composite number
The present work proposes a method for simultaneous determination of tryptophan and 5-hydroxytryptophan on the carbon-bearing electrode modified with multiwall carbon nanotubes and polyfolic acid. Analytical signals are conditioned by oxidation of tryptophan and 5–hydroxytryptophan from the complex containing polyfolic acid. Preparation of the electrode consists in the formation of the B 9 vitamin film on the surface of the carbon-bearing electrode, modified with multiwall carbon nanotubes by the method of cyclic voltammetry. The detection limit of tryptophan and 5-hydroxytryptophan is 1 × 10 –7 M.