Open AccessThe method for quantitative magnetic resonance imaging of agar phantom with contrast agent
Author(s) -
Yanurita Dwihapsari,
E. Asdiantoro,
Nurul Maulidiyah
Publication year - 2020
Publication title -
journal of physics. conference series
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 85
eISSN - 1742-6596
pISSN - 1742-6588
DOI - 10.1088/1742-6596/1572/1/012080
Subject(s) - imaging phantom , magnetic resonance imaging , contrast (vision) , distortion (music) , nuclear magnetic resonance , spin echo , exponential function , pulse sequence , signal (programming language) , materials science , physics , computer science , mathematics , optics , medicine , radiology , mathematical analysis , amplifier , optoelectronics , cmos , programming language
Magnetic Resonance Imaging (MRI) is one of the reliable instruments in medical physics for diagnostic and treatment monitoring. In MRI scanning, data were acquired using several techniques depending on the parameters being measured. Several quantitative MRI methods were conducted to obtain values of some parameters in MRI, such as spin-spin relaxation time or T 2 . T 2 -value was generally obtained using spin-echo sequence and the recent development used multiple spin-echo sequence to significantly reduce acquisition time. The quantification of T 2 is achieved by exponential fitting of echo-time with signal intensity. Although the quantification is quite straightforward, some distortion and errors were found during quantification process due to several factors. In this study T 2 quantification of agar with various concentrations was conducted and the study was focused on the processing method for T 2 quantification. The fitting methods based on mono-exponential and bi-exponential models would be applied and the results would be compared to find the best method for quantitative T 2 MRI of gel phantom. The method would also be applied in agar phantom with addition of CuSO 4 contrast agent to observe the effect of contrast agent on T 2 -value.