Open AccessIn vitro investigation of laser-induced microgrooves on titanium surface
Author(s) -
Vadim P. Veiko,
Yulia Karlagina,
Elena Egorova,
Ekaterina Zernitskaya,
Daria Kuznetsova,
Vadim Elagin,
Elena V. Zagaynova,
Г. В. Одинцова
Publication year - 2020
Publication title -
journal of physics. conference series
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 85
eISSN - 1742-6596
pISSN - 1742-6588
DOI - 10.1088/1742-6596/1571/1/012010
Subject(s) - titanium , osteon , human bone , in vitro , biomedical engineering , materials science , laser , mesenchymal stem cell , adhesion , biophysics , chemistry , anatomy , microbiology and biotechnology , cortical bone , composite material , biology , optics , biochemistry , metallurgy , medicine , physics
We developed a surface design that imitates the osteon structure of human bone tissue to improve the bio-integration of a titanium implants. Two types of subcellular-sized microgrooves were formed on VT6 (analogue 6Al-4V) titanium surface by laser processing: closed and open microgrooves. An in vitro study of the proliferation of human bone marrow mesenchymal stem cells on the formed structures was carried out, osteogenic differentiation was studied.