Open AccessMagnetic Drug-loaded Microcapsules Intergrating Photo thermal and Targeted Therapy
Author(s) -
Yu Han,
Ying Gao,
Xiaoqian Shan
Publication year - 2020
Publication title -
journal of physics. conference series
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 85
eISSN - 1742-6596
pISSN - 1742-6588
DOI - 10.1088/1742-6596/1549/3/032013
Subject(s) - mesoporous silica , materials science , chemotherapy , nanoparticle , drug , nanotechnology , magnetic nanoparticles , thermal treatment , targeted drug delivery , drug delivery , medicine , biomedical engineering , mesoporous material , pharmacology , chemistry , composite material , organic chemistry , catalysis
Compared with single chemotherapy, collaborative treatment can significantly improve the cure rate of malignant tumors, reduce the use of chemotherapy drugs and avoid the damage to the organs. The combination of Photo thermal therapy and chemotherapy has also become the most common treatment in recent years. In this article, we synthesized a kind of mesoporous silica with a large specific surface area and pore volume to encapsulate the Fe 3 O 4 nanoparticles. Owing to the unique magnetic and photo thermal properties of Fe 3 O 4 nanoparticles, the combination of PTT- chemo targeted therapy has been achieved and greatly reduces the side effects of the drugs on the human body. This novel particle will create a broader application in the future.