Open AccessSynthesis, characterization and biological evaluation studies of Cu(II) and Zn(II) complexes with gly-o-andn or gly-p-andn as primary ligand and N, N' donors as secondary ligand
Author(s) -
Nidhi Aggarwal,
Rishi Kant,
Gaurav Kumar,
Charisma James,
Suman Maji
Publication year - 2020
Publication title -
journal of physics. conference series
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 85
eISSN - 1742-6596
pISSN - 1742-6588
DOI - 10.1088/1742-6596/1531/1/012111
Subject(s) - chemistry , ligand (biochemistry) , schiff base , glyoxal , metal , zinc , transition metal , molecule , copper , combinatorial chemistry , stereochemistry , condensation reaction , polymer chemistry , organic chemistry , receptor , biochemistry , catalysis
Metal complexes with heterocyclic Schiff bases are of substantial curiosity for the chemists. Ligand modifications are easily accessible due to preparative simplicity, structural variability and tunable electronic properties. Hetero atoms like N and O when incorporated in Schiff bases play a key role at binding sites in metallobiomolecules Transition metals form an integral part of biological system and their mixed ligand complexes with Schiff bases have established their remarkable application in biocidal fields as antibacterial, antifungal, antiinflammatory and as anticancerous agents. Keeping in mind their marked biological activity, this work reports the synthesis and characterization of mixed ligand complexes of zinc and copper with Schiff base (obtained by the condensation of glyoxal with ortho and para anisidine) as primary and N, N’ donor molecules as secondary ligands.