Open AccessModulating Effect of Drug Chloramphenicol on the Aggregation Behavior of the Ionic Liquid 1-tetradecyl-3-methylimidazolium Bromide: A Conductometric Study
Author(s) -
Harsh Kumar,
Ramanjeet Kaur
Publication year - 2020
Publication title -
journal of physics. conference series
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 85
eISSN - 1742-6596
pISSN - 1742-6588
DOI - 10.1088/1742-6596/1531/1/012101
Subject(s) - chemistry , bromide , micelle , ionic liquid , critical micelle concentration , conductometry , dissociation (chemistry) , chloramphenicol , drug , inorganic chemistry , chromatography , nuclear chemistry , organic chemistry , biochemistry , pharmacology , antibiotics , aqueous solution , catalysis , medicine
In this report, the influence of addition of different wt. % of drug chloramphenicol on the aggregation phenomenon of 1-tetradecyl-3-methylimidazolium bromide (SAIL) has been extensively examined using conductometric technique at temperatures 298.15K, 308.15K, 318.15K. Utilising the values obtained from conductance measurements, the critical micelle concentration (cmc) and degree of dissociation (α) for the micelles formed in the temperature range of 298.15-318.15K at different wt. % of drug chloramphenicol in the medium have been achieved. The various thermodynamic parameters (ΔG m 0 , ΔH m 0 , ΔS m 0 ) of micellization were evaluated by conductivity measurements. Effect of additive (drug) on the aggregation behavior of the ionic liquid have been discussed.