Open AccessT2 Quantification of Agarose with Contrast Agent in Magnetic Resonance Imaging
Author(s) -
Yanurita Dwihapsari,
E. Asdiantoro,
Nurul Maulidiyah
Publication year - 2020
Publication title -
journal of physics. conference series
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 85
eISSN - 1742-6596
pISSN - 1742-6588
DOI - 10.1088/1742-6596/1505/1/012044
Subject(s) - agarose , magnetic resonance imaging , nuclear magnetic resonance , contrast (vision) , chemistry , relaxation (psychology) , spin echo , gradient echo , spin–spin relaxation , biomedical engineering , spin–lattice relaxation , chromatography , medicine , optics , radiology , physics , nuclear quadrupole resonance
Spin-spin relaxation time or T 2 is an important parameter in Magnetic Resonance Imaging (MRI) which provides information on molecular structure inside tissues, properties of human tissues and metabolites inside human body. It also contributes to clinical study by providing more information on pathological properties and delineation between healthy and malignant tissues in brain pathologies and identification of tissue abnormalities. In this study, T 2 measurement was performed by acquiring T 2 images of agarose hydrogel. T 2 -weighted imaging sequence was used with variation of agarose concentration, echo-time and repetition time. The signal intensities of samples were acquired and fitted to echo-time to obtain T 2 -value. In addition, contrast agent of CuSO 4 was mixed with agarose solution and the similar T 2 measurement was performed with variation concentration of agarose and CuSO 4 . Although some limitations were found during T 2 measurement due to acquisition and instrumental setting, T 2 quantification could provide more information about properties inside samples. The quantification could also be used for measurement of the effectiveness of contrast agent for increasing image contrast in MRI scanning.