Open AccessStudy on Medication Regularity of Sijunzi Decoction and Its Categorized Prescriptions Based on Attribute Partial Order Structure Diagram
Author(s) -
Jialin Song,
Xiaoying Han,
Meng Hui
Publication year - 2020
Publication title -
journal of physics. conference series
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 85
eISSN - 1742-6596
pISSN - 1742-6588
DOI - 10.1088/1742-6596/1453/1/012157
Subject(s) - decoction , medical prescription , traditional medicine , medicine , herb , medicinal herbs , pharmacology
Sijunzi decoction is a famous prescription in traditional Chinese medicine (TCM) for the treatment of spleen deficiency syndrome. Spleen deficiency syndrome is manifested in a variety of symptoms. Herbs can be added or replaced on the basis of Sijunzi decoction according to different symptoms, forming Sijunzi categorized prescriptions. In this paper, the medication regularity of Sijunzi decoction and its categorized prescriptions was studied based on attribute partial order structure diagram (APOSD). According to prescription-herb APOSD generated from Sijunzi decoction categorized prescriptions screened from comprehensive TCM database, it can be seen that three herbs are used in all prescriptions, i.e. Renshen, Baizhu and Fuling. Different forms of Sijunzi decoction mainly depend on whether the forth herb is Zhigancao, Chenpi-Gancao, or Gancao. The efficacy of common herbs in the prescriptions for different symptoms can be presented by prescription-herb APOSD and prescription-symptom APOSD generated from different prescription subgroups. The experimental results show that APOSD can effectively reveal the medication regularity of Sijunzi decoction and its categorized prescriptions, and it is an useful tool for theoretical study of TCM.