Open AccessBioprotective properties of nano-diamond composition at intragastric introduction to rats
Author(s) -
N. A. Lomteva,
Е. И. Кондратенко,
С. К. Касимова,
S. K. Gordeev,
A F Alykova,
О. М. Алыкова,
I. N. Zavestovskaya
Publication year - 2020
Publication title -
journal of physics. conference series
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 85
eISSN - 1742-6596
pISSN - 1742-6588
DOI - 10.1088/1742-6596/1439/1/012042
Subject(s) - lipid peroxidation , thyroid , chemistry , nanodiamond , cadmium , cadmium chloride , biochemistry , medicine , antioxidant , diamond , organic chemistry
We studied a biocompatibility and a bioprotector property of nanodiamond composites on reduction of the toxic action to cadmium salt. The experimental animal intragastric received with the help of a probe activated carbon and nanodiamond composite. We researched the rate of spontaneous and ascorbate-dependent lipids peroxidation and the reference level of malonic dialdehyde in liver, thyroid and adrenal glands tissues. So this concentration of the nanopore material at intragastric entering did not led to difference of researched parameters of the lipid peroxidation. The solution of cadmium salt developed typical for it toxic action which expressed in increase intensity of the processes of POL in liver and thyroid gland tissues. The nanopore material developed the characteristic which screened the toxic action of cadmium chloride and it was more denominated on some parameters in comparison with the effect of the intragastric entering of the activated carbon.