Open AccessSynthesis of glycidoxy spacer on the surface of magnetic nanoparticles and immobilization of albumin
Author(s) -
Д. В. Королев,
Kamil G. Gareev,
V N Zorin,
N. V. Evreinova,
V. N. Postnov,
T. N. Romanova
Publication year - 2019
Publication title -
journal of physics. conference series
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 85
eISSN - 1742-6596
pISSN - 1742-6588
DOI - 10.1088/1742-6596/1410/1/012069
Subject(s) - adsorption , albumin , nanoparticle , chemistry , magnetic nanoparticles , benzene , glycine , human serum albumin , serum albumin , nuclear chemistry , chemical engineering , chromatography , materials science , nanotechnology , organic chemistry , biochemistry , amino acid , engineering
The glycidine spacer was synthesized from three different solvents. It is shown that the samples synthesized from benzene have the highest efficiency. Human albumin was immobilized onto a glycidine spacer. A mechanism for the interaction of albumin with a glycine spacer is proposed. An analysis of the determination of albumin adsorbed by magnetic nanoparticles was performed in this work.