Open AccessAnalysis of the mineral component for cortical bone tissue by Raman spectroscopy after ovariectomy and its treatment with allogeneic hydroxyapatite
Author(s) -
Е. В. Тимченко,
П. Е. Тимченко,
Е. В. Писарева,
M. Yu. Vlasov,
Л. Т. Волова,
Yana V. Fedorova,
A. Tumchenkova,
M. Y. Gorchenkova,
A. N. Subatovich
Publication year - 2019
Publication title -
journal of physics. conference series
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 85
eISSN - 1742-6596
pISSN - 1742-6588
DOI - 10.1088/1742-6596/1400/6/066026
Subject(s) - ovariectomized rat , raman spectroscopy , cortical bone , resorption , bone tissue , chemistry , medicine , biomedical engineering , materials science , pathology , estrogen , optics , physics
In the work results of experimental researches of mineral component of cortical tissue after ovariectomy and estimation of correction using allogeneic hydroxyapatite (HAP) by the method of Raman spectroscopy are presented. A comparative analysis of bone samples from non-ovariectomized and ovariectomized animals after HAP injection was carried out using the Raman spectra. Coefficients which allow to estimate resorption of cortical tissue after ovariectomy and correction using HAP was entered. Introduction of HAP suspension showed that the consequences of ovariectomy can be almost compensated for the cortical tissue.