Open AccessThe potential of derivatives of organotin(IV) benzoate compounds in medicinal chemistry
Author(s) -
Samsuar,
Wasinton Simanjuntak,
Hardoko Insan Qudus,
Sutopo Hadi
Publication year - 2019
Publication title -
journal of physics. conference series
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 85
eISSN - 1742-6596
pISSN - 1742-6588
DOI - 10.1088/1742-6596/1338/1/012014
Subject(s) - bacteria , antibiotics , chemistry , antibiotic resistance , combinatorial chemistry , organic chemistry , microbiology and biotechnology , biochemistry , biology , genetics
This paper deals with short review about the application of organotin(IV) compounds. The discovery of bacterial resistance to antibiotics drew the attention of chemists to discover new types of chemical compounds that have the antibacterial activity to overcome the resistance. Increased antibiotic resistance is a consequence of the evolution and adaptation of microbes, caused by excessive anthropogenic antibiotic consumption. Increased cases of bacterial resistance will be a bigger problem if not treated with the discovery of new antibiotics. The discovery of medicinal chemicals may contribute to the advancement of treatment, especially antibiotic resistant. Organotin(IV) compounds are part of organometallic compounds that have been studied their pharmacological effects on several types of bacteria. The derivatives of organotin(IV) benzoate compounds proven to have biological activity against some types of bacteria. The type and structure of the ligand in the compound derivative of organotin(IV) benzoate gives the influence of different biological activity against bacteria.