Open AccessEvaluation of DNA damage and Environmental Antioxidants defense systems in type 2 diabetes mellitus Patients
Author(s) -
Ayad M.J. Al-mamoori,
Mohammed J Al-jassani,
Maher M. Khadairi,
Wasan K. Alwan,
Rasha Nayyef Ali Assi
Publication year - 2019
Publication title -
journal of physics. conference series
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 85
eISSN - 1742-6596
pISSN - 1742-6588
DOI - 10.1088/1742-6596/1294/6/062093
Subject(s) - malondialdehyde , superoxide dismutase , glutathione peroxidase , lipid peroxidation , catalase , dna damage , diabetes mellitus , medicine , antioxidant , glutathione , comet assay , type 2 diabetes mellitus , chemistry , endocrinology , oxidative stress , biochemistry , dna , enzyme
The presents study was conducted to evaluate the DNA damage markers, antioxidants makers and lipid peroxidation in type 2 diabetes mellitus patients, the results of presents study was showed the DNA damage markers such as comet length, tail length, %DNA in tail and tail moments were significantly increased at p<0.05 in diabetic patients as compared with healthy control group, Also all biochemical markers such as superoxide dismutase SOD, catalase CAT, Glutathione peroxidase GPx, Glutathione GSH and Malondialdehyde MDA were significantly elevated with diabetic patients as compared with healthy control