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2D range modulator for high-precision water calorimetry in scanned carbon-ion beams
Author(s) -
K. Holm,
Ulrich Weber,
Yuri Simeonov,
A. Krauss,
Oliver Jäkel,
Steffen Greilich
Publication year - 2020
Publication title -
physics in medicine and biology/physics in medicine and biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.312
H-Index - 191
eISSN - 1361-6560
pISSN - 0031-9155
DOI - 10.1088/1361-6560/aba6d5
Subject(s) - algorithm , analytical chemistry (journal) , materials science , computer science , chemistry , chromatography
Ionization chamber-based dosimetry for carbon-ion beams still shows a significantly higher standard uncertainty than high-energy photon dosimetry. This is mainly caused by the high standard uncertainty of the correction factor for beam quality k Q , Q 0 . Due to a lack of experimental data, the given values for k Q , Q 0 are based on theoretical calculations. To reduce this standard uncertainty, k Q , Q 0 factors for different irradiation conditions and ionization chambers (ICs) can be determined experimentally by means of water calorimetry. To perform such measurements in a spread-out Bragg peak (SOBP) for a scanned carbon-ion beam, we describe the process of creating an almost cubic dose distribution of about 6 × 6 × 6 cm 3 using a 2D range modulator. The aim is to achieve a field homogeneity with a standard deviation of measured dose values in the middle of the SOBP (over a lateral range and a depth of about 4 cm) below 2% within a scanning time of under 100 s, applying a dose larger than 1 Gy. This paper describes the optimization and characterization of the dose distribution in detail.

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