An age-specific biokinetic model for iodine
Author(s) -
R. W. Leggett
Publication year - 2017
Publication title -
journal of radiological protection
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.471
H-Index - 46
eISSN - 1361-6498
pISSN - 0952-4746
DOI - 10.1088/1361-6498/aa8d30
Subject(s) - iodine , thyroid , isotope , nuclear medicine , medicine , radiochemistry , physiology , chemistry , physics , nuclear physics , organic chemistry
This paper reviews age-specific biokinetic data for iodine in humans and extends to pre-adult ages the baseline parameter values of the author's previously published model for systemic iodine in adult humans. Compared with the ICRP's current age-specific model for iodine introduced in Publication 56 (1989, pp 45-48), the present model provides a more detailed description of the behaviour of iodine in the human body; predicts moderately higher doses to the thyroid for short-lived isotopes of iodine; predicts similar doses to the thyroid for isotopes with half-time greater than a few hours; and, for most iodine isotopes, predicts substantially higher doses to salivary glands, stomach wall, liver, and kidneys.
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