A facility for in vivo measurement of kidney and liver cadmium by neutron capture prompt gamma ray analysis
Author(s) -
D. Vartsky,
Kenneth J. Ellis,
N. S. Chen,
S.H. Cohn
Publication year - 1977
Publication title -
physics in medicine and biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.312
H-Index - 191
eISSN - 1361-6560
pISSN - 0031-9155
DOI - 10.1088/0031-9155/22/6/003
Subject(s) - imaging phantom , in vivo , cadmium , kidney , detection limit , nuclear medicine , materials science , radiochemistry , chemistry , medicine , biology , chromatography , microbiology and biotechnology , metallurgy
An in vivo method for the determination of Cd levels in human kidney and liver has been developed. The method allows detection of absolute quantities of Cd in the left kidney and Cd concentration in the liver. The limit of detection of cadmium is 2.5 mg for the left kidney and 1.8 microgram/g (wet weight) for the liver, for a localized dose of 670 mrem. The effects of patient positioning, organ geometry and liver-kidney interference on the measurement have been investigated using an Alderson phantom.
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