Relative Transmissibility of an R5 Clade C Simian‐Human Immunodeficiency Virus Across Different Mucosae in Macaques Parallels the Relative Risks of Sexual HIV‐1 Transmission in Humans via Different Routes | Zendy

Agnès L. Chénine | Zendy; Nagadenahalli B. Siddappa | Zendy; Victor G. Kramer | Zendy; Gaia Sciaranghella | Zendy; Robert A. Rasmussen | Zendy; Sandra J. Lee | Zendy; Michael Santosuosso | Zendy; Mark C. Poznansky | Zendy; Vijayakumar Velu | Zendy; Rama Rao Amara | Zendy; Chris Souder | Zendy; Daniel C. Anderson | Zendy; François Villinger | Zendy; James G. Else | Zendy; Francis J. Novembre | Zendy; Elizabeth Strobert | Zendy; Shawn P. O’Neil | Zendy; W. Evan Secor | Zendy; Ruth M. Ruprecht | Zendy

Open Access

Relative Transmissibility of an R5 Clade C Simian‐Human Immunodeficiency Virus Across Different Mucosae in Macaques Parallels the Relative Risks of Sexual HIV‐1 Transmission in Humans via Different Routes

Author(s) -

Agnès L. Chénine,

Nagadenahalli B. Siddappa,

Victor G. Kramer,

Gaia Sciaranghella,

Robert A. Rasmussen,

Sandra J. Lee,

Michael Santosuosso,

Mark C. Poznansky,

Vijayakumar Velu,

Rama Rao Amara,

Chris Souder,

Daniel C. Anderson,

François Villinger,

James G. Else,

Francis J. Novembre,

Elizabeth Strobert,

Shawn P. O’Neil,

W. Evan Secor,

Ruth M. Ruprecht

Publication year - 2010

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/651274

Subject(s) - simian immunodeficiency virus , macaque , virus , biology , virology , transmission (telecommunications) , immunology , sexual transmission , lentivirus , viral disease , simian , human immunodeficiency virus (hiv) , microbicide , paleontology , electrical engineering , engineering

Worldwide, approximately 90% of all human immunodeficiency virus (HIV) transmissions occur mucosally; almost all involve R5 strains. Risks of sexual HIV acquisition are highest for rectal, then vaginal, and finally oral exposures.

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