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Cytomegalovirus Retinitis in a Patient Treated with Anti--Tumor Necrosis Factor Alpha Antibody Therapy for Rheumatoid Arthritis
Author(s) -
Georg Haerter,
Burkhard Manfras,
Yvonne de JongHesse,
H. Wilts,
Thomas Mertens,
Peter Kern,
MariePaule Schmitt
Publication year - 2004
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/425123
Subject(s) - medicine , cytomegalovirus retinitis , valganciclovir , rheumatoid arthritis , retinitis , ganciclovir , immunology , arthritis , infliximab , antibody , gastroenterology , tumor necrosis factor alpha , human cytomegalovirus , virus
Anti-tumor necrosis factor alpha (anti-TNF- alpha ) antibodies have been used for the treatment of chronic inflammatory diseases such as rheumatoid arthritis (RA) and psoriasis arthritis. Such antibody therapies result in a severe interference with the patient's immune system. Increased rates of upper respiratory tract infection, reactivation of latent tuberculosis, and other systemic infectious diseases have been reported among patients receiving anti-TNF- alpha antibodies.

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