Residual active granzyme B in cathepsin C–null lymphocytes is sufficient for perforin-dependent target cell apoptosis
Author(s) -
Vivien R. Sutton,
Nigel J. Waterhouse,
Kylie A. Browne,
Karin Sedelies,
Annette Ciccone,
Desiree Anthony,
Aulikki Koskinen,
Arno Müllbacher,
Joseph A. Trapani
Publication year - 2007
Publication title -
the journal of experimental medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 8.483
H-Index - 448
eISSN - 1540-9538
pISSN - 0022-1007
DOI - 10.1084/jem2042oia3
Subject(s) - perforin , granzyme b , cathepsin e , biology , apoptosis , granzyme , cathepsin s , null cell , microbiology and biotechnology , immunology , cancer research , cathepsin b , t cell , cell culture , genetics , antigen , immune system , biochemistry , cd8 , cathepsin o , enzyme
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom