Open AccessBak activators get in the groove
Author(s) -
Mitch Leslie
Publication year - 2011
Publication title -
the journal of cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.414
H-Index - 380
eISSN - 1540-8140
pISSN - 0021-9525
DOI - 10.1083/jcb.1941iti2
Subject(s) - biology , activator (genetics) , cousin , groove (engineering) , microbiology and biotechnology , connection (principal bundle) , genetics , gene , engineering , structural engineering , mechanical engineering , archaeology , history
![Figure][1] A model shows how a portion of the activator Noxa (yellow) settles into the groove on Bak.The protein Bak belongs to a molecular hit squad that spurs apoptosis. [Dai et al.][2] reveal that Bak has to make the right connection before it can kill cells.Bak and its cousin Bax
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom