Open AccessApratoxin chaperones EGFR to its destruction
Author(s) -
Ben Short
Publication year - 2009
Publication title -
the journal of cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.414
H-Index - 380
eISSN - 1540-8140
pISSN - 0021-9525
DOI - 10.1083/jcb.1854iti1
Subject(s) - biology , chaperone (clinical) , microbiology and biotechnology , computational biology , pathology , medicine
A small toxin from a cyanobacterium pushes growth-promoting proteins such as the EGF receptor (EGFR) along an unusual path to destruction, report [Shen et al.][1]Several oncogenic proteins, including EGFR, p53, and cyclindependent kinases are collectively known as Hsp90 client proteins due to
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom