Open AccessBirth control for centrioles
Author(s) -
Mitch Leslie
Publication year - 2009
Publication title -
the journal of cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.414
H-Index - 380
eISSN - 1540-8140
pISSN - 0021-9525
DOI - 10.1083/jcb.1842iti2
Subject(s) - centriole , biology , microbiology and biotechnology , organelle , dna replication , mechanism (biology) , cell cycle , replication (statistics) , copying , mitosis , genetics , dna , cell , virology , physics , quantum mechanics
Like DNA, centrioles need to duplicate only once per cell cycle. [Rogers et al.][1] uncover a long-sought mechanism that limits centriole copying, showing that it depends on the timely demolition of a protein that spurs the organelles' replication.![Figure][2] Cells unable to break down
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