Open AccessFHL1 adds some muscle
Author(s) -
Ben Short
Publication year - 2008
Publication title -
the journal of cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.414
H-Index - 380
eISSN - 1540-8140
pISSN - 0021-9525
DOI - 10.1083/jcb.1836iti5
Subject(s) - biology , mutant , transcription factor , cytosol , microbiology and biotechnology , anatomy , genetics , biochemistry , gene , enzyme
![][1] Unlike the wild-type protein (left), mutant FHL1 (right, green) forms cytosolic aggregates (arrows) that sequester NFATc1 (red).[Cowling et al.][2] report how to build muscle mass with FHL1. The protein partners with and activates the transcription factor, NFATc1. Encouraging
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