Open AccessA weak signaler gets in close
Author(s) -
Richard Robinson,
Ruth Williams
Publication year - 2008
Publication title -
the journal of cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.414
H-Index - 380
eISSN - 1540-8140
pISSN - 0021-9525
DOI - 10.1083/jcb.1825iti3
Subject(s) - biology , endosome , microbiology and biotechnology , blocking (statistics) , receptor , genetics , computer science , computer network
![Graphic][1] Nuclear accumulation of STAT3 (left) is prevented by blocking endosome shuttling of c-Met (right). When c-Met can't shout, it moves closer to get its signal heard, according to [Kermorgant and Parker][2].c-Met is the plasma membrane receptor for hepatocyte growth
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