Open AccessPhosphorylation for break repair
Author(s) -
Nicole LeBrasseur
Publication year - 2008
Publication title -
the journal of cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.414
H-Index - 380
eISSN - 1540-8140
pISSN - 0021-9525
DOI - 10.1083/jcb.1812iti2
Subject(s) - biology , phosphorylation , microbiology and biotechnology , dna repair , dna , phosphate , genetics , biochemistry
![Graphic][1] The retention of MRN (red) at dsDNA breaks (green) is lost when MDC1 phosphorylation sites are mutated (right). Aconstitutive, phosphate-based interaction between two repair proteins may help provide instant, well-coordinated repair of double-stranded DNA (dsDNA) breaks
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