Open AccessNew exit: caspase-1 for secretion
Author(s) -
Richard Robinson
Publication year - 2008
Publication title -
the journal of cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.414
H-Index - 380
eISSN - 1540-8140
pISSN - 0021-9525
DOI - 10.1083/jcb.1806rr1
Subject(s) - secretion , biology , microbiology and biotechnology , cytokine , signal transduction , secretory protein , signal peptide , immunology , biochemistry , peptide sequence , gene
Acaspase activates secretion of many inflammatory response proteins without signal sequences, say Martin Keller, Hans-Dietmar Beer, and colleagues (Swiss Federal Institute of Technology, Zurich, Switzerland), revealing a new pathway for secretion.The cytokine interleukin-1α (IL-1α) has no
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