Open AccessBacktracking on FAK
Author(s) -
Mitch Leslie
Publication year - 2008
Publication title -
the journal of cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.414
H-Index - 380
eISSN - 1540-8140
pISSN - 0021-9525
DOI - 10.1083/jcb.1801iti2
Subject(s) - focal adhesion , biology , decipher , microbiology and biotechnology , backtracking , cell adhesion , adhesion , signal transduction , cell , bioinformatics , genetics , computer science , algorithm , chemistry , organic chemistry
![Graphic][1] Because their back ends get stuck, cells missing FAK and Pyk2 stretch until they break. To decipher how cells crawl, researchers have knocked out a key signaling protein known as focal adhesion kinase (FAK), which relays messages from the cell surface. But the results of
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