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Three dimensional electron spin resonance (ESR) imaging of internal organs in living mice
Author(s) -
Masumizu Toshiki,
Fujii Kanae,
Kohno Masahiro,
Nagai Soichi,
Odagaki Yuji,
Imanari Mamoru,
Mori Akitane,
Packer Lester
Publication year - 1998
Publication title -
iubmb life
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.132
H-Index - 113
eISSN - 1521-6551
pISSN - 1521-6543
DOI - 10.1080/15216549800204242
Subject(s) - electron paramagnetic resonance , in vivo , magnetic resonance imaging , nuclear magnetic resonance , site directed spin labeling , nitroxide mediated radical polymerization , spin (aerodynamics) , preclinical imaging , kidney , spin echo , chemistry , materials science , medicine , biology , physics , radiology , endocrinology , thermodynamics , microbiology and biotechnology , radical polymerization , copolymer , polymer
In viva electron spin resonance imaging (ESR imaging) was applied to living mice after peroral administration of a nitroxide radical spin probe. A 3D ESR imaging procedure was applied in vivo in order to obtain the exact distribution of the spin probe in a living animal. The imaging pictures demonstrated that the administered spin probe was firstly located in the stomach, then delivered to the liver, kidney and heart of the animal.